EFFECTS OF ORAL 20% SUCROSE ON SEVERITY OF PAIN DURING VENIPUNCTURE IN PREMATURE NEONATES IN MOTAHARI HOSPITAL OF URMIA, IRAN, 2019-2020

Prevention or reduction of pain is especially important in premature infants who
are subjected to more repetitive painful procedures that are necessary for their survival and uncontrolled
pain in this type of infant leads to permanent damage to the components of growth and cognitive
development and changes in response to subsequent painful stimuli. The present study aims to study the
effects of oral 20% sucrose on severity of pain during venipuncture in premature neonates in Motahari
hospital of Urmia, Iran, 2019-2020.
Materials & Methods: In this a double-blind randomized controlled trial, 100 premature infants
admitted to the neonatal intensive care unit of Motahhari Educational and Medical Center in Urmia in
the second half of 2019) were assigned to three groups of sucrose 20% (50 infants) and control group
(50 infants). Then, the behavioral response of infants with NIPS instrument before, 2 and 7 minutes after
the vasodilation process was evaluated and recorded as a processor by direct observation of the infant
by the researcher.
Results: The results showed that the mean score of pain before and 2 and 7 minutes after the intervention
in sucrose group was equal to (4.78±0.91), (3.18±1.15) and (3.02±1.02) and in the control group
(4.84±0/79). 4), (4.94±0.79) and (4.72±0.96). The trend of variable response (pain scores) was not the
same over time between the two groups of sucrose, and control, and statistically significant differences
were observed in the mean pain scores at different times (P <0.001). Prior to the intervention, the mean
of all three groups was approximately the same and in the control group, during the following periods,
the averages were almost similar and did not change significantly with each other.
Conclusion: According to the findings of the present study, oral solutions of sucrose 20% is effective
in relieving pain in infants after venipuncture. Because this method is simple, safe, and easy to use, it is
recommended for clinical routine use as an effective intervention