THE RELATIONSHIP BETWEEN BMI AND IUI (INTRAUTERINE INSEMINATION) IN WOMEN WITH CLOMIPHENE RESISTANCE REFERRED TO FATEMEH ZAHRA INFERTILITY CENTER

The relationship between obesity and reproductive function is well known and the obese women have no response to usual treatment and need assisted reproductive technique (ART). In this study, the pregnancy outcome of women resistant to Clomiphene Citrate (CC) with different BMI was evaluated in IUI cycle.
Materials & Methods: This cross-sectional study was conducted on 107 infertile CC-resistant women who were referred to Babol Infertility Center and were candidate for IUI. Patients' BMI was classified as normal, overweight, and obese. All women received CC 100 mg from the third day of menstruation. It continued with HMG 75mg for three days and more according to the size of follicles, and then IUI was performed. The relationship between different BMI groups with IUI outcome was examined. The p-value <0.05 was considered significant.
Results: The mean age of the subjects was 25.5 ± 3.5 years and the mean duration of infertility was 4.8± 2.1 years and the mean BMI of the subjects was 28.7 ± 3.7. About 37% of the patients underwent CC + HMG. The overall pregnancy rate was 24% (24). There was no significant relationship between the number of pregnancies and the BMI classification. There was a significant relationship between infertility type (primary or secondary), regular or irregular menstrual cycle with BMI (p = 0.002 and p=0.004, respectively).
Conclusion: Positive IUI outcome was compared in the different classifications of BMI; however, a significant relationship was observed between the irregular menstrual cycles and primary infertility with BMI classifications.