EVALUATION OF THE HISTOPATHOLOGIC CHARACTERISTICS OF GASTROINTESTINAL TUMORS IN ENDOSCOPY SAMPLES IN URMIA IMAM KHOMEINI HOSPITAL

Cancer is the most common cause of death in developing and developed countries,
accounting for nearly 13% of world death. In Iran, gastrointestinal cancers are common. Therefore, this
study was conducted to evaluate the gastrointestinal tract tumors in Urmia Imam Khomeini hospital.
Material & Methods: In this cross-sectional study, pathology reports of 741 patients with
gastrointestinal tumor were evaluated.
Results: Of 741 reported tumor, 705 cases (95.14%) were malignant, 36 cases (4.85%) were benign.
61.8% of patients with malignant tumors were men and 38.1% were women. The mean age of patients
with malignant tumors was 60.2±13.35 and the mean age of patients with benign tumors was
47.7±10.49. The most abundant malignant tumor was adenocarcinoma with 481 cases (68.22%)
followed by squamous cell carcinoma with 137 cases (19.43%) and the most frequent benign tumor was
lipoma(52.7% of cases). The malignant tumors were observed mostly in the ages of 71 or higher (232
cases (32.9%)). In the evaluation of anatomical location of the malignant tumors, in esophagus, the
precise location was not reported in most cases (63.7%). In the stomach, the cardia with 29.27%, in the
small intestine, the duodenum with 66.6%, and in the colorectal region, the rectum with 41.9% were the
most involved locations.
Conclusion: The results of our study indicated that the most abundant malignant tumor of the
gastrointestinal tract was adenocarcinoma and the most abundant benign tumor was lipoma. Malignant
tumors were observed mostly in men while benign tumors were mostly observed in women. The high
frequency of malignant tumors in the ages of 71 and higher indicates the importance of early-onset
screening for the prevention of malignant tumors in older ages.