Does Ganoderma lucidum reduce obesity?

Appetite is regulated in humans through the
interaction between the central nervous system and
peripheral hormones. This process involves a delicate
balance in external stimuli, circulating satiating and
appetite-stimulating hormones, and correct functioning
of neuronal signals. Any changes in this equilibrium can
cause an imbalance in energy intake versus expenditure,
often leading to overeating and potential weight gain
resulting in overweight or obesity (1).
Drug therapies with some antibiotics and prebiotics
have been used to manage obesity and related metabolic
disorders, but to no avail. Fungi are important because
of their high fiber. One of the most intriguing medicinal
mushrooms is the Basidiomycete fungus Ganoderma
lucidum, which has been utilized for centuries to
promote health and longevity. Ganoderma lucidum can
be employed for weight loss and fitness with regular
consumption. It is one of the most amazing and
miraculous fungi found in nature in different colors,
such as red, white, and bright yellow. Ganoderma fungi
have different species, each of which is suitable for
specific conditions. This fungus is among the most
effective herbal medicines applied in traditional Chinese
medicine and is still considered by countless people.
Ganoderma is a herbal medicine used to bring health and
well-being (2). Ganoderma contains active compounds
that affect the body's metabolism. By increasing
metabolism, more energy is consumed, preventing fat
accumulation and obesity. When metabolism increases
to a desired extent, it will lead to weight loss.
Ganoderma allows more oxygen to be delivered to the
body's cells through the blood, thereby elevating
metabolism in the body (3).