Fakhim, H and Vaezi, A and Badali, H and Meis, J.F and Dannaoui, E and Prakash, A and Chowdhary, A (2017) In Vitro Interactions of Echinocandins with Triazoles against Multidrug- Resistant Candida auris. Antimicrobial Agents and Chemotherapy, 61 (11). pp. 1-5.
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Abstract
We determined the in vitro interactions between echinocandins and azoles against 10 multidrug-resistant Candida auris strains by use of a microdilution checkerboard technique. Our results suggest synergistic interactions between micafungin and voriconazole with fractional inhibitory concentration index (FICI) values of 0.15 to 0.5, and we observed indifferent interactions when micafungin was combined with fluconazole (FICI, 0.62 to 1.5). Combinations of caspofungin with fluconazole or voriconazole exhibited indifferent interactions. No antagonism was observed for any combination.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | in vitro interactions, azoles, echinocandins, Candida auris |
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | Unnamed user with email gholipour.s@umsu.ac.ir |
| Date Deposited: | 30 Jul 2019 06:17 |
| Last Modified: | 30 Jul 2019 06:17 |
| URI: | http://eprints.umsu.ac.ir/id/eprint/5590 |
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